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Miniaturizing immunoassays to the nanoliter scale reduces reagent and sample consumption, making it possible, for example, to perform one mouse, one PK studies that minimize animal use and biological variation in preclinical studies and maximize data quality
Only a qualified healthcare professional can determine whether a GLP-1 RA is appropriate for an individual patient, based on a full clinical assessment
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The side-effect profile is gastrointestinal-dominant: nausea (44% in SUSTAIN trials), diarrhea (31%), constipation (24%), and vomiting (18%) (Sorli et al., Diabetes Care , 2017)
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