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Lan H, Vassileva G, Corona A, Liu L, Baker H, Golovko A, et al

However, the most significant weight loss typically occurs as you reach the higher, more effective doses

These effects often improve within a few weeks as your body becomes more familiar with the medication, but it may take longer for some people

[DOI] [PubMed] [Google Scholar] 2.Abbott R.D., Donahue R.P., MacMahon S.W., Reed D.M., Yano K

The exact reason isnt fully understood, but the dose-dependent pattern across multiple medications suggests it may be related to how these drugs interact with nerve signaling at higher concentrations

By activating both receptors, oxyntomodulin increases energy expenditure, reduces appetite, promotes weight loss, and improves glucose tolerance, showcasing the therapeutic potential of this dual mechanism [79]