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It is characterized by abdominal obesity, high blood pressure, high blood sugar, and abnormal cholesterol levels
Direct stimulation of these receptors may contribute to nausea and emesis, particularly during the initial weeks of treatment or following dose escalation
Meta-analyses suggest that GLP-1RAs can lead to an average BMI reduction of 12 kg/m 2 , a decrease in waist circumference of several centimeters, and total weight loss of 5%7% in some studies (85)
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