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When blood pressure is elevated, there is a constant, increased force stretching arteries beyond a healthy limit

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Teleologically, increased GLP-1 secretion plays a role as an ileal brake to maintain a normal speed of energy metabolism by decelerating gastric emptying and suppressing food intake

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However, the use of ginseng-derived saponins has been associated with increased secretion of GLP-1, more clinical studies in humans are needed to fully understand the in-human regulation of GLP-1 by ginseng