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Huang WT, Chuang SS
The majority of human data comes from pharmacological challenge studies rather than therapeutic trials
Kidney Dysfunction: While the kidneys do not directly excrete vitamin B12 efficiently, impaired renal function may lead to elevated serum B12 levels by reducing the clearance of B12-binding proteins or altering their metabolism, thereby contributing to B12 accumulation 8
Furthermore, taurine, an amino acid found in Goji berries, lowers hyperglycemia-induced apoptosis in retinal cells by a variety of mechanisms, including caspase-3 inhibition and increased production of protective genes [301]
Insulin resistance and the polycystic ovary syndrome revisited: an update on mechanisms and implications
NRF2 orchestrates the upregulation of several antioxidant genes reliant on GSH, including GSR, solute carrier family 7 member 11 (SLC7A11), glutamatecysteine ligase catalytic subunit (GCLC), and glutamatecysteine ligase modifier subunit, as well as metabolic detoxification genes such as aldehyde dehydrogenase 1 family member A1 and aldoketo reductase family 1 member C1 in cancer cells [66]
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