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While these products demonstrate measurable benefits, they suffer from inherent limitations in absorption and systemic distribution

J Neurol Neurosurg Psychiatry

[DOI] [PMC free article] [PubMed] [Google Scholar] 9.De Andrade K.Q., Moura F.A., Dos Santos J.M., De Arajo O.R., De Farias Santos J.C., Goulart M.O.F

Surveys across various regions in China among adults aged 1865 years show an annual prevalence of headache as 28.5%, with most cases being primary migraines frequently seen in middle-aged women (Yu et al., 2013, 2012, 2011)

Their concerns are not small ones

The following sections will provide a detailed overview of research findings across these domains