They overall are less healthy with a lower lean body mass
(FDA Access Data) In real life, that often looks like smaller portions feeling more reasonable, fewer intrusive thoughts about food, and less grazing late in the day
These medications combine the effects of a GLP-1 receptor agonist with an agonist for GIP, another hormone produced by the small intestine
The Trial The ATTAIN-MAINTAIN trial enrolled patients who had achieved substantial weight loss that had plateaued while taking weekly injectable GLP-1s in the SURMOUNT-5 trial
This muscle loss can impair metabolic health, reduce physical strength, and accelerate aging processes
Good protein sources include: Lean meats, poultry, and fish Eggs and dairy products Legumes such as lentils, chickpeas, and beans Nuts and seeds Dietary fibre , particularly soluble and fermentable types, promotes GLP-1 secretion through multiple mechanisms