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Consequently, the action of thiamine protects cells and tissues from the harmful effects of oxidative stress [52]

Daver NG, Pollyea DA, Garcia JS, Jonas BA, Yee KWL, Fenaux P, Assouline S, Vey N, Olin R, Roboz GJ, Tafuri A, Visani G, Kirschbrown W, Green C, Ma C, Dail M, Wang J, Ott MG, Mobasher M, Phuong P, Hong WJ, Konopleva MY, Andreeff M

In some cases, staying at the same dose for two to four weeks before increasing may reduce the intensity of digestive side effects, including constipation

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