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The further addition of GCGR agonism in retatrutide introduces Gs-cAMP signalling in hepatocytes, brown adipose tissue, and the central nervous system cell types with limited or no GLP-1R or GIPR expression expanding the tissue scope of the compound's action profile

B12 allows for the creation of haem which is essential for the production of functional red blood cells

Impacts of polystyrene microplastic on the gut barrier, microbiota and metabolism of mice

Neurological function, inflammatory infiltration, oligodendrocyte progenitor cells (OPCs), and mature oligodendrocytes were measured in the brains of EAE mice

This sensation, called formication, stems from changes in the nervous system during menopause

Gut microbiota dysbiosis is linked to higher risk of mental health condition and psychiatric diseases (118, 119)