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Among ~13,000 detected genes, only 126 were differentially expressed between semaglutide- and vehicle-treated animals (47 upregulated, 79 downregulated) with no signature of alterations in metabolic-or growth-related processes, indicating relatively mild hepatic transcriptional reprogramming (Fig

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doi: 10.3390/coatings11050501 139 WangKYangXWuZWangHLiQMeiHet al

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" In arriving at the arbitrary species-wide definitions of enlarged and normal hearts, this ACVIM Consensus Statement panel also has ignored the vast body of veterinary literature on scientifically establishing reference intervals and decision thresholds denoting the cutpoints between healthy and diseased dogs