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However, GLP-1 administration has been shown to result in hypoglycemia when concomitantly administered with intravenous dextrose (25) or with sulfonylureas (26)

Understanding any negative effects of current practice and how GPs can better meet the needs of this marginalised group is key to improving safety and care, they concluded

Although typically advantageous for heart and vascular well-being, such variations may intermittently interfere with regulating blood flow in certain persons and could result in muscle aches or cramps