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The overall discontinuation rate due to adverse events was approximately 10%, which compares favorably to most compounds in this class

10.29271/jcpsp.2019.06.502 163 ManfredaV.EleonoraD

The photoprotective properties of increased melanin also potentially reduce the risk of certain types of skin cancer and sun damage in susceptible individuals, while minimizing the need for UV exposure to obtain the desired tanned appearance

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[DOI] [PMC free article] [PubMed] [Google Scholar] 332.Huber KM, Gallagher SM, Warren ST, Bear MF

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