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The most common side effects in the retatrutide group were gastrointestinal symptoms, which were dose-dependent and mostly mild to moderate in severity

During our earlier efforts to identify orally available peptides ( 25 ), we recognized the important role that carboxylic acid substituents played in activating the GLP-1R

2020;151(suppl 1):45-50

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Traditional pharmacological agents have demonstrated renewed potential in LC by modulating the autophagy-ferroptosis axis through diverse and sometimes unexpected mechanisms