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As expected, compared to those healthy control subjects, the tissues of breast cancer patients exhibit significantly increased lipid peroxidation, which is dependent on functional polymorphism of GPx1 [82]

New small-molecule approaches that selectively inhibit both TNF- and IL-1 activities could provide greater clinical activity

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Tumor-associated inflammation involves complex interactions between epithelial and stromal cells, which can sometimes result in epigenetic changes that drive malignancy or even initiate tumorigenesis

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