Given that more than half of total knee and hip arthroplasty patients meet criteria for obesity or morbid obesity, weight loss strategies, particularly pharmacologic approaches like GLP-1 receptor agonists, are becoming increasingly relevant in optimizing surgical outcomes and mitigating complications
Some researchers split the protocol across two vials instead, reconstituting each with 1 mL for a 10 mg/mL concentration and using one vial for the first 2.5 weeks before starting the second
Storage Instructions: Keep out of reach of children
Other patients also experienced clinical improvements, including a 6 year old boy with severe diabetes, ketosis (accumulation of ketones, a term first used by the German chemist Leopold Gmelin - figure 5), heavy glycosuria and malnutrition (de Levia, Brugus, de Leiva-Prez)
Standard-dose protocols may produce stronger appetite suppression, but they can also create a higher likelihood of noticeable side effects during escalation
Participants underwent physical examination and electrocardiogram at screening, week 20, week 52 and week 104