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GLP-1 signaling demonstrates potent endoplasmic reticulum (ER) stress-modulating effects in diverse pathological contexts
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Roughly 45% of large employers now include at least one anti-obesity medication on their formulary, up from about 25% in 2023
Clinical trials show average weight reduction of 1522% of body weight over 68 weeks significantly beyond what diet and exercise alone typically produce for most patients
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