The Billon 2025 paper (PMID 41421047) introduced SLU-PP-915 as an "orally active" sibling specifically because the parent SLU-PP-332 "lacks oral bioavailability." Despite that, the most common vendor formats are oral capsules and tablets products without published evidence that they produce systemic ERR agonism in humans
Lobo, V., Patil, A., Phatak, A., & Chandra, N
This compound is not approved by the FDA, ANVISA, or any regulatory agency for human or veterinary use
TB-500: The Cellular Migration and Remodeling Director TB-500 is a synthetic form of thymosin beta-4, a peptide associated with cell migration and tissue repair
Fortunately, there is increasing evidence that oral B12 supplements are just as good as injections for raising blood levels in most people ( Vegetarians and vegans are usually advised to take at least 10 mcg per day, or at least 2,000 mcg once per week ( However, some doctors still prefer the use of injections
The answer depends on where you live, whether you have medical insurance, and how you plan to get the injection