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The discrepancies can be due to different design of the studies and also the duration of L-carnitine consumption, in such a way that it was on average 82 days in the Kitano and co-workers study, while in the present study it was consumed for 6 weeks (42 days) by almost 85% of patients

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The criteria for liver injury were vacuolization of hepatocytes and pyknotic hepatocyte nuclei, activation of Kupffer cells, and enlargement of sinusoids