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Health Conditions : Certain health conditions, such as kidney or liver disease, may affect how your body processes Vitamin B12 injections

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Definition: High serum vitamin B12 is defined by a rate above 950 pg/ml (701pmol/l), which corresponds by biological standards, to the upper limit of biological normality

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Many patients with type 2 diabetes take metformin long-term, and studies have shown it can interfere with B12 absorption in the terminal ileum

However, the IM route was the top-ranked statistically but without clinical significance