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Addressing Specific Hunger Patterns If a patient experiences intense head hunger or cravings that the GLP-1 is not fully suppressing, the stimulant effect of phentermine might be used to target those specific neurological triggers

Takako et al., 2008

One important wrinkle: if a GLP-1 is coverable under standard Part D for one of these indications, it cannot be obtained through the Bridge for weight management

total dose used per 16week cycle stays under the 10 mg supplied

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In the key STEP-1 trial (N=1,961), once-weekly subcutaneous semaglutide 2.4 mg produced 14.9% mean body weight loss at 68 weeks versus 2.4% with placebo (P standards for compounded sterile preparations set enforceable accuracy requirements (USP General Chapter 797, Pharmaceutical Compounding, Sterile Preparations)