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In contrast, the number and area of TRAP-positive cells, and the average osteoclast area indicated by F-actin staining were significantly reduced after the SP treatment, showing a dose-dependent manner (Fig

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In this study, we examine how diminished GPX4 function may be a critical event in triggering oxytosis/ferroptosis to perpetuate or initiate the neurodegenerative diseases and assess the possible therapeutic importance of oxytosis/ferroptosis in neurodegenerative disorders