i didn't lose weight on semaglutide Woman Loses 82lbs As Alternative to Bariatric Surgery How Semaglutide Aids Weight Loss:

Taking more frequent injections would disrupt this carefully calibrated steady state and could lead to unpredictable hormone levels in your system, potentially causing unnecessary side effects without improving outcomes

Drugs That Can Cause Thyroid Conditions Hormones, such as those produced by your thyroid, interact with each other, and many medications you take can disrupt your thyroid or thyroid medication

Penetration through the skin barrier is limited, particularly for larger molecules, and results depend heavily on the delivery vehicle and formulation

Its essential to follow instructions carefully to ensure the best results

Outcomes at one year can be comparable to the injectable when the daily protocol is followed consistently - the variable is adherence, not the drug itself

Update (2026): This 2018 note covers LY3298176 (tirzepatide) at an early phase