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After the procedure, an early keratinocyte proliferation occurs, increasing melanin transcutaneous elimination

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p53 is associated with the two key kinases of ataxia telangiectasia and rad3-related protein-checkpoint kinase 1 pathway [45] that induce the transcription of cell cycle suppressor p21 gene and delay damaged G1 cells from entering S phase, preventing new start events at the beginning of the duplication process and slowing down the branching processes of reproduction of UV-irradiated cells in the S phase

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En casos de lesin aguda algunos protocolos reparten la dosis en: 2 veces al da (maana + noche) para mantener niveles estables

doi: 10.1016/j.canlet.2019.04.004 49 MayJLKouriFMHurleyLALiuJTommasini-GhelfiSJiYet al