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Avoid combining with NSAIDs, which may counteract its healing effects

doi: 10.1111/nph.12304 5 ChengM.-C.KoK.ChangW.-L.KuoW.-C.ChenG.-H.LinT.-P

Athletes who routinely use ibuprofen after training may experience reduced muscle adaptation over time

Its needs can change based on the season, stress, diet, and more

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Considerations: Proper spray technique (appropriate angle, avoiding the septum) Alternating nostrils per dose Using a saline rinse periodically to support nasal mucosal health Discontinuation and route change if persistent irritation develops Patients with allergic rhinitis, chronic sinusitis, or significant septal deviation may be poor candidates for nasal delivery and should be considered for injection or oral spray instead