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These changes can be just as important as weight loss, especially during maintenance phases

In the Phase 2 trial, the most commonly reported adverse events were gastrointestinal in nature including nausea, vomiting, diarrhoea, and constipation consistent with the side effect profile seen with other GLP-1-based therapies

Urbina J et al

References U.S

The trade-off is greater dose flexibility and often lower cost, especially with compounded formulations

(The number of prescriptions exceeds the number of patients because prescription refills and renewals are counted separately.) Another indication of weight-loss drugs rapid uptake globally comes from the financial statements of their manufacturers