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This review synthesizes current knowledge on HS epidemiology, clinical features and molecular mechanisms driving its development and progression, with a focus on the pathogenic role of adipose tissue, and specifically of adipokines, on inflammation and tissue destruction

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Immune regulatory mechanisms of M2 macrophage polarization and efferocytosis in diabetic kidney disease: an integrated screening study with therapeutic implications

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Importantly, animal reproductive toxicity does not necessarily predict human outcomes , and the mechanisms observed in these studies may not translate directly to human physiology