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Some physicians prescribe it longer, and research supports extended use in certain cases, but the fundamental problem remains: phentermine is fighting your biology with a blunt instrument, and your biology eventually fights back

Cited studies PMID 36303408 "LGD-4033 and MK-677 use impacts body composition, circulating biomarkers, and skeletal muscle androgenic hormone and receptor content: A case report." ( Physiological Reports , 2022)

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The US Anti-Doping Agency (ADA) states that because it has not been extensively studied in humans, "no-one knows if there is a safe dose, or if there is any way to use this compound safely to treat specific medical conditions"

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