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In addition, based on the study of betaine in terms of genome methylation, this mechanism may involve the up-regulation of genes involved in de novo synthesis and fatty acid oxidation

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Abstract This study aimed to assess the possible consequences of spirulina (SP) and/or L-carnitine (L-car) on the prevention of primordial follicular reserve depletion and the preservation of ovarian follicular structure and function in a rat model of premature ovarian insufficiency (POI)