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While diagnostic uses for measuring total hemoglobin mass or pulmonary diffusion capacity remain permitted, using CO to artificially increase oxygen-carrying capacity is now explicitly banned

doi: 10.2337/db14-1577 44 ChoiEYangJJiGEParkMSSeongYOhSWet al

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In the brainstem, it activates neurons in the area postrema and NTS that relay visceral fullness signals