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In obesity, elevated leptin levels promote Th1 and Th17 polarization, impair regulatory T-cell function, and enhance autoreactive immune responses, while hypoadiponectinemia removes a key anti-inflammatory brake [34,35]

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Taken together with AC/FC reduction by HF treatments in this study, carnitine metabolic changes might be not only distinct prognostic biomarkers, but also be therapeutic targets for HF

Human decidual natural killer cells are a unique NK cell subset with immunomodulatory potential