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Bonnelle V, Ham TE, Leech R, Kinnunen KM, Mehta MA, Greenwood RJ, et al

Are GLP-1s only for celebrities

Glucose Partitioning: Cross-activates Insulin/IGF-1 Hybrid Receptors on muscle cells, driving GLUT4 translocation and glucose uptake independently of insulin levels

Tokai J Exp Clin Med, 10: 379-384

The studies have demonstrated that GLP-1R is also expressed in nuclei controlling food intake, such as the arcuate nucleus (ARC) and paraventricular thalamic nucleus (PVN)

Another study showed myo-inositol is similarly effective to Metformin for improving fasting insulin, insulin resistance, androgen levels, and body mass index (BMI), but with a much lower risk for adverse effects