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Mol Med Rep 23(2):1 Yan J, Fu Q, Cheng L, Zhai M, Wu W, Huang L, Du G (2014) Inflammatory response in Parkinsons disease

The earliest sign of response is reduced shedding at 4 to 8 weeks, but visible new growth requires 8 to 16 weeks and meaningful density change takes 4 to 6 months

Restricted cubic spline (RCS) with four knots at the 5th, 35th, 65th, and 95th percentiles were further used to identify potential nonlinearities in these associations

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Statistical values for ototoxin were omitted from figure legends because it is established that they cause a dose-dependent decrease in hair cell survival, in other words, we know that a dose-response curve for neomycin only will be statistically significant