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If semaglutide prevents or delays these conditions, the medication may save money over time despite its high upfront cost

These values inform whether the medication is appropriate and provide a reference point for ongoing monitoring

Deborah Horn, director of obesity medicine at UTHealth Houston, who has consulted for Lilly, told me over email

At the 12 mg dose, 93% of participants achieved at least 5% weight loss

GLP-1 medications improve insulin sensitivity in liver cells, reduce oxidative stress, and activate cellular cleaning processes like macroautophagy that help remove excess fat 19

Monitor for mood changes and seek prompt evaluation if concerning symptoms develop