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Sources Jiang Y, et al

36 Despite limited evidence, the federal drug authority (FDA) has recommended avoidance of GLP-1RA medication use among individuals who have any history of familial thyroid cancer or genetic predisposition to multiple endocrine neoplasia

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Study results have been mixed so far, and while weight loss can be significant, results are dependent on a range of variables, such as participants, type of drug used, comorbidities, length of use and target outcomes

After an initial 60 weeks on Zepbound at the MTD, participants either continued on the MTD, reduced the dose to 5 mg, or received a placebo