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For instance, in a 2021 study, 80 percent of adults who took phentermine over the course of six months lost at least five percent of their body fat, with no major side effects (18)

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So if you handled semaglutide well, there's a good chance you'll handle tirzepatide well too, especially with the slow dose escalation

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Frequently Asked Questions Q: Can I switch from GLP-1 to a dual agonist if Im not losing enough weight

The documented protocol is monotherapy for exactly this reason, and the honest comparison to make is not Retatrutide plus X but Retatrutide versus X, which is what the comparison article covers