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The slow ladder lets the gut adapt, which is why side effects are dose-dependent and mostly early

In terms of tolerability, tirzepatide generally causes fewer gastrointestinal side effects, making it a better option for those sensitive to nausea, while Semaglutide GLP-1 may cause mild to moderate gastrointestinal issues like nausea and diarrhea, which usually subside over time

A medically supervised program should protect the patients long-term health, not simply push the fastest possible weight loss

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Marzioni M, Alpini G, Saccomanno S, Candelaresi C, Venter J, Rychlicki C, et al