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In addition to excessive intake of dietary supplements, parenteral administration of vitamin B12 may be another cause of excess, which is likely associated with an immune system response to produce anti-TC II antibodies

10.1016/j.ebiom.2017.03.046 85 KalmbachK.RobinsonL

While they can reduce insulin resistance, they can also lower your blood sugar or insulin levels too much

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Getting this wrong can easily derail an entire study

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