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In addition, due to the ability of metformin to cross the placenta, continued use of metformin for GDM during pregnancy still raises concerns about its safety and potential adverse effects on the fetus

Bone resorption by osteoclasts

Other outcomes included major adverse cardiovascular events (MACE) (cardiovascular mortality, all-cause mortality, stroke, and myocardial infarction), changes in metabolic parameters, and adverse events

The foods to avoid on GLP-1 agonists apply equally to retatrutide

Diabetes Obes Metab 2011;13:348356

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