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The antioxidant response element (ARE) is a cis-acting enhancer sequence located in the promoter region of numerous genes involved in detoxification and cytoprotection (122124)

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doi:10.1111/j.1469-8749.2008.02053.x

People with pernicious anemia or people who cannot absorb vitamin B 12 from their intestines will need injections of vitamin B 12 every one to three months indefinitely

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