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Improved insulin sensitivity: By modulating nicotinamide metabolism and influencing NNMT, the compound may reduce insulin resistance, thereby promoting better glucose management

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Bibliography Arillotta et al., 2023

Lancet Lond Engl 394:121130 Frias JP, Nauck MA, Van J, Benson C, Bray R, Cui X, Milicevic Z, Urva S, Haupt A, Robins DA (2020) Efficacy and tolerability of tirzepatide, a dual glucose-dependent insulinotropic peptide and glucagon-like peptide-1 receptor agonist in patients with type 2 diabetes: A 12-week, randomized, double-blind, placebo-controlled study to evaluate different dose-escalation regimens

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34.67 16.30 ng/dL) [169]