retatrutide clinical trial results 2024 Lilly orforglipron oral GLP-1 phase 3 weight loss New clinical trial results show

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The 2mg dose produced 8.7% average weight loss

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doi: 10.1172/jci.insight.133429 146 SalamehTSRheaEMTalbotKBanksWA

GLP-1 drugs have the potential to disrupt that model, because users are not simply eating less, they are eating differently. YouGov research suggests consumers using the drugs are increasing their intake of vegetables, vitamins and fish or seafood by up to 38%

In the United States, prescribing information for all medications licensed for obesity that act on the CNS, including the GLP-1RAs liraglutide 3 mg (Saxenda) and semaglutide 2.4 mg (Wegovy), must include the recommendation of monitoring for depression and suicidal ideation 231