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The success with GLP-1 drugs has also prompted researchers to start investigating in detail the physiology of GLP-1 in the gut and the brain

Hristakeva, S., Liaukonyte, J., and Feler, L

This is roughly the same amount of weight that patients on Mounjaro lose over the course of treatment

A GLP-1R agonist increases PCSK1 expression and markers of cell fate in a subcluster of cells

Key questions remain around access, long-term use, and how healthcare can manage these costs while delivering downstream value