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Evening cortisol spikes suppress melatonin, destabilize glucose, disrupt SCFA rhythms, and weaken satiety signals, driving nighttime snacking

Gynecomastia does occasionally come with symptoms such as nipple or breast tenderness, swelling, and increased sensitivity

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The once-weekly cycle can create energy fluctuations that mirror the drug concentration curve, with fatigue peaking alongside drug concentration and then returning in a different form as levels drop

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