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Most projections point to continued expansion well into the next decade, with some estimating the market could exceed $125 billion by 2033

Generally in the U.S., healthcare technologies and services are considered cost-effective if theyre below $150,000 per QALY

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Uthman et al

In 2025, the company reported a -1.73% YoY (Jan-Dec25) decline in revenue, reflecting portfolio dynamics: Entyvio ($6.14B) continues to anchor growth in inflammatory bowel disease, Takhzyro ($1.44B) shows steady momentum in rare diseases, while Gattex/Revestive ($913.56M) remains a solid contributor in gastrointestinal disorders partially offset by generic pressure and loss of exclusivity in some legacy products