These factors indicate that the GLP-1 RA group is more severely affected by diabetes compared to the DPP-4i group, and the GLP-1 RA group may thus be subject to residual confounding associated with higher fracture risk
Autoimmune Disease Research: Interesting but Inconclusive Small studies across autoimmune conditions have explored inflammatory markers and symptoms, but effects on disease activity are inconsistent and strongly confounded
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High uric acid directly inhibits insulin signalling and induces insulin resistance