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Zdzieblik, D., et al
MTHFR variants and methylation dysfunction have been implicated in: Depression and anxiety Bipolar disorder Schizophrenia Chronic fatigue and fibromyalgia Recurrent pregnancy loss and infertility Cardiovascular and cerebrovascular disease Neurodegenerative disorders such as Alzheimers disease Supporting methylation through targeted nutrition and appropriate forms of folate can improve neurotransmitter synthesis, reduce oxidative stress, and enhance overall neurological stability
Sci Rep 5:11276
Quick Reference: Standard Protocol Self-reported starting doses begin around 0.25 mg 3x weekly for 2-4 weeks to assess tolerance, before increasing to 0.5 mg 3x weekly
A skin sensitivity test is recommended before the administration
Vitamin B12 is found in many other multivitamins and supplements
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