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Keywords: Breast cancer, colorectal cancer, IGF1, lung cancer, prostate cancer, second primary cancer Introduction Within the last 40 years, cancer survival rates have doubled in the UK 1, mainly due to advances in treatment, and the increased detection of cancer at an early stage 2

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The effect of ALDH2 expression and rs671 mutation on ferroptosis of SH-SY5Y cells The results of our CCK-8 experiment demonstrated that the apoptosis inhibitor Z-vad, the necrosis inhibitor Nec-1, and the ferroptosis inhibitor Fer-1 reduced the harmful effects of MPP + on SH-SY5Y cells