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They exert their antitumor effects through multiple mechanisms, including epigenetic modification, inhibition of key signaling pathways, and modulation of the tumor microenvironment ( Figure 3 )

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Micrographs are representative images

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An animal experimental study showed that activation of 2-AR can alleviate IR induced by a high-fat diet (HFD) in MASLD mice, suggesting that adrenergic receptors play a critical role in the pathogenesis of MASLD 66

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