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NNMT inhibitors require fasted-state dosing to eliminate nicotinamide competition this is mechanism-driven, not a general peptide rule

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Note, for BPC 157, a persistent effect is mandatory, as it can prevent amphetamine disturbances, reverse already advanced disturbances, and counteract amphetamine reverse tolerance even after a very long period (i.e., 46 days) [70,153] and even substitute the loss of dopamine neurons (MPTP) (note, BPC 157 counteracted tremor, rigor, akinesia, and also MPTP-mortality) [69]

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