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Your healthcare provider will need to assess whether you meet the criteria for GLP-1 receptor agonist therapy, which typically includes having type 2 diabetes with inadequate control on metformin alone (HbA1c above target) according to NICE guideline NG28

Safer, Evidence-Based Alternatives Available Through the NHS NICE-recommended semaglutide (Wegovy) and MHRA-authorised tirzepatide (Mounjaro) are regulated, evidence-based options for weight management available through NHS specialist services

It fundamentally alters how the body processes and stores energy at multiple points in the metabolic cascade

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Brand-name tirzepatide costs approximately $1,400-$1,600 per month

SSRIs increase serotonin broadly, and the downstream effect on 5-HT2C receptors specifically suppresses sexual desire and delays or prevents orgasm